MOXA NPort 6650I-16-G2 Introduction
The Moxa NPort 6650I-16-G2 Serial to Ethernet Device Server offers an efficient way to connect serial devices to modern Ethernet infrastructures while maintaining compatibility with existing industrial systems. Designed for applications where reliability and communication continuity are essential, it helps organizations reduce upgrade costs and simplify network management across distributed environments.
Represented by part number NPort 6650I-16-G2, the device features 16 serial interfaces supporting RS-232/422/485 standards, allowing seamless integration with a wide range of industrial equipment. High-speed communication is supported through 2 to 4 Gigabit RJ45 Ethernet ports, with 2kV isolation creating flexible deployment options for expanding networks. The rugged metal body enhances durability for industrial use, while microSD support up to 2 TB offers convenient local storage and data logging functionality. Its -10 to 60°C temperature capability allows deployment in harsh industrial environments. Positioned within the Terminal Servers category, it provides dependable connectivity for industrial communication systems.
MOXA NPort 6650I-16-G2 Certifications

MOXA NPort 6650I-16-G2 Features
- Ethernet Ports: 2 x 10/100/1000M RJ45
- 2 kV Isolation
- Serial Standards: RS-232/422/485
- SD Slot: microSD card Up to 2 TB (high speed, 25 Mbps)
- Metal body
- -10 to 60°C operating temperature
Place your order with confidence for the MOXA NPort 6650I-16-G2 Serial to Ethernet Device Server at a competitive price for industrial solutions, by purchasing online or inquiring through the website at our Middle East branches (UAE (Dubai, Abu Dhabi), KSA (Al Khobar, Riyadh), Kuwait, Qatar, and Oman). Our customer-focused approach ensures a straightforward buying process.
| serial-to-ethernet : Interface | |
| 10/100Mb RJ45 (Megabit) Ports | Yes: 2 ports (up to 4) |
| Digital Output Channels | - |
| Alarm Contact Channels | - |
| Magnetic Isolation Protection | 1.5 kV (built-in) |
| Protocols | TLS, SSH |
| serial-to-ethernet : Serial port specifications | |
| Flow Control | None, RTS/CTS, DTR/DSR, RTS Toggle, XON/XOFF |
| serial-to-ethernet : Communication details | |
| Wireless Standards | - |
| Maximum data transfer speed | - |
| Maximum direct range | - |
| serial-to-ethernet : Serial Interface | |
| Number of Ports | 16 Ports |
| Serial Standards | RS-232/422/485 |
| Connector | 8-pin RJ45 |
| Console Port | - |
| serial-to-ethernet : General | |
| Management | ARP, DHCP Client, DNS, HTTPS, ICMP, IPv4/IPv6, SMTP, SMTPS, SNMPv1/v2c/v3, SNTP, TCP/IP, UDP, WINS |
| MTBF | 29,185 hrs |
| Compatible operating systems | - |
| Fixed TTY Drivers | macOS versions: 14, 13, 12, and 11 |
| Linux Real TTY Drivers | Kernel versions 6.x, 5.x, and 4.x |
| Automatic Reboot Trigger | Built-in WDT |
| serial-to-ethernet : Serial Communication Parameters | |
| Data Bits | 5, 6, 7, 8 |
| Stop Bits | 1, 1.5, 2 |
| Parity | None, Even, Odd, Space, Mark |
| Baudrate | 50 bps to 921.6 kbps (supports non-standard baudrates) |
| Isolation | 2 kV |
| serial-to-ethernet : Power Requirements | |
| Connection | - |
| Input Voltage | AC models: 100 to 240 VAC, DC models: ±48 VDC (20 to 72 VDC, -20 to -72 VDC) |
| Input Current | 330 mA (max.) |
| serial-to-ethernet : Security | |
| Security | HTTPS (TLS 1.2/1.3), SNMPv3, SSHv2 |
| Encryption | HTTPS: ECC-256, ECC-384, ECC-521, RSA-1024, RSA-2048, RSA-3072, RSA-4096, AES-128, AES-256, CHACHA20, SHA-256, SHA-384, HMAC, SSH: ECC-256, ECC-384, ECC-521, RSA-2048, AES-128, AES-256, SHA-256, SHA-384, HMAC SNMPv3: AES-128, SHA-256, SHA-384, Secure OP mode: HTTPS: ECC-256, ECC-384, ECC-521, RSA-1024, RSA-2048, RSA3072, RSA-4096, AES-128, AES-256, CHACHA20, SHA-256, SHA-384, HMAC, Config import/export: AES-256, SHA-256, HMAC |
| Authentication | Local database, RADIUS, TACACS+ |
| serial-to-ethernet : Serial Signals | |
| RS-232 | TxD, RxD, RTS, CTS, DTR, DSR, DCD, GND |
| RS-422 | Tx+, Tx-, Rx+, Rx-, GND |
| RS-485-4w | Tx+, Tx-, Rx+, Rx-, GND |
| RS-485-2w | Data+, Data-, GND |
| serial-to-ethernet : Features and capabilities | |
| Display | - |
| serial-to-ethernet : Physical Characteristics | |
| Installation | Desktop, Rack mounting (RK-43-01, included in the box) |
| Standards and Certifications | EMC, EMI, EMS, NEMA TS2, IEC 62368-1, UL 62368-1, EN 62368-1, IEC 60068-2-6, ISTA 1A, RoHS, CRoHS, WEEE, Telcordia Standard SR-332, Telcordia SR-332 Issue 4 |
| Housing | Metal |
| Operation Humidity | 5 to 95% (non-condensing) |
